Clinicopathological Analysis of Anterior-Superior Mediastinal Masses

Background: The mediastinum is the space between two lungs, bounded anteriorly by sternum and posteriorly vertebral column. A spectrum of neoplastic non-neoplastic lesions can arise in mediastinum.
 Methods: total 14 cases were retrospectively retrieved from Histopathology department. had histopathological diagnosis either image guided, thorocoscopic, transbronchial or excision biopsies.
 Results: majority (43% n=6) thymic origin, which included both thymoma group lesion like cysts. 3 B3 1 case AB. lymphoid include Hodgkin lymphoma (14.3%; n=2) non-Hodgkin (7.1%; n=1). mesenchymal (21.4%; n=3) lipoma, solitary fibrous tumor schwannoma accounts for one each. rare ectopic parathyroid adenoma a metastatic papillary carcinoma n=1) also reported.
 Conclusion: mediastinal mass pose difficulties due to its wide clinicopathologic clinician, radiologists pathologist. multimodal approach with examination immunohistochemistry help arriving at an accurate diagnosis.